
In recent years, the landscape of weight loss and diabetes treatment has dramatically shifted. The spotlight has now turned to Mounjaro (tirzepatide), a groundbreaking injectable medication initially approved by the FDA in May 2022 for treating type 2 diabetes. Mounjaro is gaining widespread recognition for its powerful secondary benefit: significant weight loss. With the rising rates of obesity and related metabolic disorders in the United States, Mounjaro represents a promising new frontier in chronic disease management.
In this article, we explore Mounjaro, how it works, and the clinical evidence supporting its effectiveness. Hopefully, we can help you decide if trying Mounjaro is the right choice for you.
What is Mounjaro, and Why is It Different?
Mounjaro contains tirzepatide, a once-weekly injectable medication that activates two hormonal pathways:
- GLP-1 (glucagon-like peptide-1) receptor: Stimulates insulin production and reduces appetite.
- GIP (glucose-dependent insulinotropic polypeptide) receptor: Enhances the body’s insulin response and improves fat metabolism.
This dual-action mechanism is what differentiates Mounjaro from other GLP-1 receptor agonists like Ozempic or Wegovy. By targeting both receptors, Mounjaro offers improved blood sugar control while promoting dramatic weight loss, making it an appealing option for patients with type 2 diabetes and individuals dealing with obesity.
This is why many Americans are now choosing to buy Mounjaro from Canada through trusted prescription referral services such as 365 Script Care.
The Health Crisis: Obesity and Diabetes in the United States
The United States faces a growing public health crisis related to metabolic health:
- According to the Centers for Disease Control and Prevention (CDC), over 42% of U.S. adults are obese.
- More than 37 million Americans live with diabetes, and approximately 90-95% of them have type 2 diabetes.
- Obesity is closely linked to an increased risk of heart disease, stroke, type 2 diabetes, and certain cancers—all among the leading causes of preventable death.
These numbers emphasize the urgent need for effective medications that address both diabetes and weight management, which is where Mounjaro plays a critical role.
Clinical Research Supporting Mounjaro
The SURMOUNT-1 trial, one of the largest clinical studies of tirzepatide, demonstrated Mounjaro’s unparalleled efficacy:
- Participants taking the 15 mg dose lost an average of 22.5% of their body weight over 72 weeks.
- In contrast, Ozempic users averaged 15% weight loss in similar studies.
- Mounjaro also helped lower blood pressure, improve cholesterol levels, and reduce markers of inflammation.
A person weighing 250 pounds could expect to lose over 55 pounds using Mounjaro under medical supervision. These results rival or even exceed outcomes from bariatric surgery, positioning Mounjaro as a potentially game-changing non-surgical option.
Affordability Barriers in the U.S. Healthcare System
Despite its impressive clinical results, the cost of Mounjaro in the United States presents a major barrier to access. The retail price for a one-month supply exceeds $1,000 USD, and many insurance plans do not cover it for weight loss indications. With over 27 million uninsured Americans and millions more underinsured, cost becomes a deciding factor in access to care.
This is where Canadian prescription referral services like 365 Script Care come into the picture. U.S. consumers can buy Mounjaro from Canada at prices up to 60% lower than U.S. retail, without compromising on quality or safety.
How Mounjaro Works
Mounjaro is administered via a once-weekly injection and is available in several dosages ranging from 2.5 mg to 15 mg. Patients typically start on the lowest dose and gradually increase it based on tolerance and treatment goals.
The drug works by:
- Stimulating insulin release in response to food
- Suppressing glucagon, which prevents unnecessary sugar production in the liver
- Slowing stomach emptying to enhance feelings of fullness
- Interacting with appetite regulation centers in the brain to reduce caloric intake
As a result, Mounjaro offers sustained weight loss and better control over blood glucose levels.
Common and Rare Side Effects
As with any medication, side effects are possible. The most commonly reported include:
- Nausea
- Diarrhea
- Vomiting
- Constipation
- Decreased appetite
These side effects often diminish over time. Less common but serious risks include:
- Pancreatitis
- Gallbladder problems
- Kidney issues
- Thyroid C-cell tumors (in animal studies)
Patients should consult a healthcare provider to assess their risk profile before starting Mounjaro.
Long-Term Benefits and Health Outcomes
Clinical evidence suggests that weight loss of just 5–10% can significantly improve health outcomes. According to the American Diabetes Association:
- A 5–7% weight loss can reduce the risk of type 2 diabetes by 58% in high-risk individuals.
- Weight loss also improves blood pressure, lipid levels, and overall quality of life.
Mounjaro makes these outcomes achievable for patients who previously struggled with weight management, even after diet and exercise interventions.
U.S. Patients Turn to 365 Script Care
365 Script Care is a Canadian prescription referral service that connects U.S. patients with licensed pharmacy partners. The benefits include:
- Substantial cost savings compared to U.S. prices
- Easy online ordering process
- Prescription verification for safety
- Medications are shipped directly to your home in the U.S.
- Professional customer support for any questions
This allows patients to buy Mounjaro from Canada legally and safely, without the financial burden of inflated domestic pricing.
A Realistic Alternative to Surgery
For many individuals, bariatric surgery has been the only viable solution for substantial weight loss. However, surgery comes with its risks, high costs, and potential complications. Mounjaro, by contrast, offers:
- A non-invasive alternative
- Lower financial and medical risk
- The ability to reverse course if side effects become problematic
For patients looking to avoid surgery but still achieve transformational weight loss, Mounjaro offers hope backed by clinical data.

What Patients Are Saying
Real-world experiences from patients using Mounjaro are overwhelmingly positive:
“I’ve lost 40 pounds in 6 months. My A1C dropped from 8.2 to 6.3, and I feel like I have my life back.” – Maria R., New York
“I couldn’t afford the U.S. prices. Buying from Canada through 365 Script Care saved me hundreds each month.” – David L., Georgia
These testimonials reinforce the growing demand and trust in international prescription referral services.
Getting Started with Mounjaro
To purchase Mounjaro from Canada, U.S. patients need a valid prescription from their healthcare provider. Once submitted to 365 Script Care, the process typically involves:
- Verification of the prescription by a licensed Canadian pharmacy partner
- Order confirmation and payment
- Secure shipping via international courier
Orders usually arrive within 7–14 business days, depending on location and customs clearance.
Final Thoughts: A Path Forward
Mounjaro offers a new, evidence-based solution for one of the most pressing health issues in America: obesity and type 2 diabetes. With its dual mechanism of action, significant weight loss outcomes, and accessibility through services like 365 Script Care, this medication is poised to reshape how we manage chronic conditions.
For patients seeking a safe, affordable, and effective treatment plan, the ability to buy Mounjaro from Canada through a licensed pharmacy affiliate may be a game-changer in their health journey.
Read more: The Relationship Between Exercise and Diabetes
Tags: diabetes, fat loss, Mounjaro, Supplements, type 2 diabetes, weight loss